Today's research in agentic AI centers on three interconnected challenges: reasoning robustness under scale, safety and verifiability in multi-step execution, and the coupling of memory, control, and oversight in autonomous systems. On the reasoning side, work on Large Reasoning Models reveals a paradox, additional inference-time computation does not reliably improve solution quality, with errors accumulating in forest-like structures that make first solutions often superior to alternatives, suggesting test-time scaling requires fundamentally different approaches than parameter scaling. Safety work spans two complementary directions: evaluating whether agents can be exploited through sequences of individually benign actions (AgentHazard's 73% attack success rate indicates current systems remain highly vulnerable), and detecting covert multi-agent coordination through activation-space probing, establishing that deception manifests as localized token-level signals. The field increasingly recognizes that effective agents require structured constraints, ontology-based grounding that enforces domain consistency and regulatory compliance, hierarchical orchestration that prevents cascading error propagation in information-seeking tasks, and process-level verification that audits intermediate states rather than final answers. Across these themes runs a methodological shift from aggregate benchmarks to fine-grained task-level diagnostics: whether through Item Response Theory adapted for coding agents, rubric failure taxonomies, or step-wise trajectory annotation, researchers are moving toward understanding not whether agents succeed but where and why they fail. The coupling of episodic memory with verifiable action, learning from experience while maintaining auditability, emerges as a core architectural requirement, with successful systems integrating feedback loops that refine both orchestration policies and role-specific behaviors simultaneously.
Cole Brennan
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Cognitive Behavioral Therapy (CBT) aims to identify and restructure automatic negative thoughts pertaining to involuntary interpretations of events, yet existing counseling agents struggle to identify and address them in dialogue settings. To bridge this gap, we introduce STEP, a dataset that models CBT counseling by explicitly reflecting automatic thoughts alongside dynamic, action-level counseling sequences. Using this dataset, we train STEPPER, a counseling agent that proactively elicits automatic thoughts and executes cognitively grounded interventions. To further enhance both decision accuracy and empathic responsiveness, we refine STEPPER through preference learning based on simulated, synthesized counseling sessions. Extensive CBT-aligned evaluations show that STEPPER delivers more clinically grounded, coherent, and personalized counseling compared to other strong baseline models, and achieves higher counselor competence without inducing emotional disruption.
Reliable pattern recognition systems should exhibit consistent behavior across similar inputs, and their explanations should remain stable. However, most Explainable AI evaluations remain instance centric and do not explicitly quantify whether attribution patterns are consistent across samples that share the same class or represent small variations of the same input. In this work, we propose a novel metric aimed at assessing the consistency of model explanations, ensuring that models consistently reflect the intended objectives and consistency under label-preserving perturbations. We implement this metric using a pre-trained BERT model on the SST-2 sentiment analysis dataset, with additional robustness tests on RoBERTa, DistilBERT, and IMDB, applying SHAP to compute feature importance for various test samples. The proposed metric quantifies the cosine similarity of SHAP values for inputs with the same label, aiming to detect inconsistent behaviors, such as biased reliance on certain features or failure to maintain consistent reasoning for similar predictions. Through a series of experiments, we evaluate the ability of this metric to identify misaligned predictions and inconsistencies in model explanations. These experiments are compared against standard fidelity metrics to assess whether the new metric can effectively identify when a model's behavior deviates from its intended objectives. The proposed framework provides a deeper understanding of model behavior by enabling more robust verification of rationale stability, which is critical for building trustworthy AI systems. By quantifying whether models rely on consistent attribution patterns for similar inputs, the proposed approach supports more robust evaluation of model behavior in practical pattern recognition pipelines. Our code is publicly available at https://github.com/anmspro/ESS-XAI-Stability.
This paper identifies a structural limitation in current multimodal AI architectures that is topological rather than parametric. Contrastive alignment (CLIP), cross-attention fusion (GPT-4V/Gemini), and diffusion-based generation share a common geometric prior -- modal separability -- which we term contact topology. The argument rests on three pillars with philosophy as the generative center. The philosophical pillar reinterprets Wittgenstein's saying/showing distinction as a problem rather than a conclusion: where Wittgenstein chose silence, the Chinese craft epistemology tradition responded with xiang (operative schema) -- the third state emerging when saying and showing interpenetrate. A cruciform framework (dao/qi x saying/showing) positions xiang at the intersection, executing dual huacai (transformation-and-cutting) along both axes. This generates a dual-layer dynamics: chuanghua (creative transformation as spontaneous event) and huacai (its institutionalization into repeatable form). The cognitive science pillar reinterprets DMN/ECN/SN tripartite co-activation through the pathological mirror: overlap isomorphism vs. superimposition collapse in a 2D parameter space (coupling intensity x regulatory capacity). The mathematical pillar formalizes these via fiber bundles and Yang-Mills curvature, with the cruciform structure mapped to fiber bundle language. We propose UOO implementation via Neural ODEs with topological regularization, the ANALOGY-MM benchmark with error-type-ratio metric, and the META-TOP three-tier benchmark testing cross-civilizational topological isomorphism across seven archetypes. A phased experimental roadmap with explicit termination criteria ensures clean exit if falsified.
Evaluating retail strategies before deployment is difficult, as outcomes are determined across multiple stages, from seller-side persuasion through buyer-seller interaction to purchase decisions. However, existing retail simulators capture only partial aspects of this process and do not model cross-stage dependencies, making it difficult to assess how early decisions affect downstream outcomes. We present RetailSim, an end-to-end retail simulation framework that models this pipeline in a unified environment, explicitly designed for simulation fidelity through diverse product spaces, persona-driven agents, and multi-turn interactions. We evaluate RetailSim with a dual protocol comprising human evaluation of behavioral fidelity and meta-evaluation against real-world economic regularities, showing that it successfully reproduces key patterns such as demographic purchasing behavior, the price-demand relationship, and heterogeneous price elasticity. We further demonstrate its practical utility via decision-oriented use cases, including persona inference, seller-buyer interaction analysis, and sales strategy evaluation, showing RetailSim's potential as a controlled testbed for exploring retail strategies.
Learners' use of video controls in educational videos provides implicit signals of cognitive processing and instructional design quality, yet the lack of scalable and explainable predictive models limits instructors' ability to anticipate such behavior before deployment. We propose a scalable, interpretable pipeline for predicting population-level watching, pausing, skipping, and rewinding behavior as proxies for cognitive load from video content alone. Our approach leverages multimodal large language models (MLLMs) to compute embeddings of short video segments and trains a neural classifier to identify temporally fine-grained interaction peaks. Drawing from multimedia learning theory on instructional design for optimal cognitive load, we code features of the video segments using GPT-5 and employ them as a basis for interpreting model predictions via concept activation vectors. We evaluate our pipeline on 77 million video control events from 66 online courses. Our findings demonstrate that classifiers based on MLLM embeddings reliably predict interaction peaks, generalize to unseen academic fields, and encode interpretable, theory-relevant instructional concepts. Overall, our results show the feasibility of cost-efficient, interpretable pre-screening of educational video design and open new opportunities to empirically examine multimedia learning theory at scale.
Deep research agents (DRAs) integrate LLM reasoning with external tools. Memory systems enable DRAs to leverage historical experiences, which are essential for efficient reasoning and autonomous evolution. Existing methods rely on retrieving similar trajectories from memory to aid reasoning, while suffering from key limitations of ineffective memory evolution and increasing storage and retrieval costs. To address these problems, we propose a novel Memory Intelligence Agent (MIA) framework, consisting of a Manager-Planner-Executor architecture. Memory Manager is a non-parametric memory system that can store compressed historical search trajectories. Planner is a parametric memory agent that can produce search plans for questions. Executor is another agent that can search and analyze information guided by the search plan. To build the MIA framework, we first adopt an alternating reinforcement learning paradigm to enhance cooperation between the Planner and the Executor. Furthermore, we enable the Planner to continuously evolve during test-time learning, with updates performed on-the-fly alongside inference without interrupting the reasoning process. Additionally, we establish a bidirectional conversion loop between parametric and non-parametric memories to achieve efficient memory evolution. Finally, we incorporate a reflection and an unsupervised judgment mechanisms to boost reasoning and self-evolution in the open world. Extensive experiments across eleven benchmarks demonstrate the superiority of MIA.
AI coding agents operate in a paradox: they possess vast parametric knowledge yet cannot remember a conversation from an hour ago. Existing memory systems store text in vector databases with single-channel retrieval, require cloud LLMs for core operations, and implement none of the cognitive processes that make human memory effective. We present SuperLocalMemory V3.3 ("The Living Brain"), a local-first agent memory system implementing the full cognitive memory taxonomy with mathematical lifecycle dynamics. Building on the information-geometric foundations of V3.2 (arXiv:2603.14588), we introduce five contributions: (1) Fisher-Rao Quantization-Aware Distance (FRQAD) -- a new metric on the Gaussian statistical manifold achieving 100% precision at preferring high-fidelity embeddings over quantized ones (vs 85.6% for cosine), with zero prior art; (2) Ebbinghaus Adaptive Forgetting with lifecycle-aware quantization -- the first mathematical forgetting curve in local agent memory coupled to progressive embedding compression, achieving 6.7x discriminative power; (3) 7-channel cognitive retrieval spanning semantic, keyword, entity graph, temporal, spreading activation, consolidation, and Hopfield associative channels, achieving 70.4% on LoCoMo in zero-LLM Mode A; (4) memory parameterization implementing Long-Term Implicit memory via soft prompts; (5) zero-friction auto-cognitive pipeline automating the complete memory lifecycle. On LoCoMo, V3.3 achieves 70.4% in Mode A (zero-LLM), with +23.8pp on multi-hop and +12.7pp on adversarial. V3.2 achieved 74.8% Mode A and 87.7% Mode C; the 4.4pp gap reflects a deliberate architectural trade-off. SLM V3.3 is open source under the Elastic License 2.0, runs entirely on CPU, with over 5,000 monthly downloads.
We study the problem of trajectory optimization in settings where the system dynamics are unknown and it is not possible to simulate trajectories through a surrogate model. When an offline dataset of trajectories is available, an agent could directly learn a trajectory generator by distribution matching. However, this approach only recovers the behavior distribution in the dataset, and does not in general produce a model that minimizes a desired cost criterion. In this work, we propose Drifting MPC, an offline trajectory optimization framework that combines drifting generative models with receding-horizon planning under unknown dynamics. The goal of Drifting MPC is to learn, from an offline dataset of trajectories, a conditional distribution over trajectories that is both supported by the data and biased toward optimal plans. We show that the resulting distribution learned by Drifting MPC is the unique solution of an objective that trades off optimality with closeness to the offline prior. Empirically, we show that Drifting MPC can generate near-optimal trajectories while retaining the one-step inference efficiency of drifting models and substantially reducing generation time relative to diffusion-based baselines.
We address the port-selection problem in fluid antenna multiple access (FAMA) systems with multi-port fluid antenna (FA) receivers. Existing methods either achieve near-optimal spectral efficiency (SE) at prohibitive computational cost or sacrifice significant performance for lower complexity. We propose two complementary strategies: (i) GFwd+S, a greedy forward-selection method with swap refinement that consistently outperforms state-of-the-art reference schemes in terms of SE, and (ii) a Transformer-based neural network trained via imitation learning followed by a Reinforce policy-gradient stage, which approaches GFwd+S performance at lower computational cost.
What kind of internal organization would allow an artificial agent not only to adapt its behavior, but to sustain a history-sensitive perspective on its world? I present a minimal architecture in which a slow perspective latent $g$ feeds back into perception and is itself updated through perceptual processing. This allows identical observations to be encoded differently depending on the agent's accumulated stance. The model is evaluated in a minimal gridworld with a fixed spatial scaffold and sensory perturbations. Across analyses, three results emerge: first, perturbation history leaves measurable residue in adaptive plasticity after nominal conditions are restored. Second, the perspective latent reorganizes perceptual encoding, such that identical observations are represented differently depending on prior experience. Third, only adaptive self-modulation yields the characteristic growth-then-stabilization dynamic, unlike rigid or always-open update regimes. Gross behavior remains stable throughout, suggesting that the dominant reorganization is perceptual rather than behavioral. Together, these findings identify a minimal mechanism for history-dependent perspectival organization in artificial agents.
Agents equipped with search tools have emerged as effective solutions for knowledge-intensive tasks. While Large Language Models (LLMs) exhibit strong reasoning capabilities, their high computational cost limits practical deployment for search agents. Consequently, recent work has focused on distilling agentic behaviors from LLMs into Small Language Models (SLMs). Through comprehensive evaluation on complex multi-hop reasoning tasks, we find that despite possessing less parametric knowledge, SLMs invoke search tools less frequently and are more prone to hallucinations. To address this issue, we propose \policy, a lightweight fine-tuning approach that explicitly trains SLMs to reliably retrieve and generate answers grounded in retrieved evidence. Compared to agent distillation from LLMs, our approach improves performance by 17.3 scores on Bamboogle and 15.3 scores on HotpotQA, achieving LLM-level results across benchmarks. Our further analysis reveals that adaptive search strategies in SLMs often degrade performance, highlighting the necessity of consistent search behavior for reliable reasoning.
We present Springdrift, a persistent runtime for long-lived LLM agents. The system integrates an auditable execution substrate (append-only memory, supervised processes, git-backed recovery), a case-based reasoning memory layer with hybrid retrieval (evaluated against a dense cosine baseline), a deterministic normative calculus for safety gating with auditable axiom trails, and continuous ambient self-perception via a structured self-state representation (the sensorium) injected each cycle without tool calls. These properties support behaviours difficult to achieve in session-bounded systems: cross-session task continuity, cross-channel context maintenance, end-to-end forensic reconstruction of decisions, and self-diagnostic behaviour. We report on a single-instance deployment over 23 days (19 operating days), during which the agent diagnosed its own infrastructure bugs, classified failure modes, identified an architectural vulnerability, and maintained context across email and web channels -- without explicit instruction. We introduce the term Artificial Retainer for this category: a non-human system with persistent memory, defined authority, domain-specific autonomy, and forensic accountability in an ongoing relationship with a specific principal -- distinguished from software assistants and autonomous agents, drawing on professional retainer relationships and the bounded autonomy of trained working animals. This is a technical report on a systems design and deployment case study, not a benchmark-driven evaluation. Evidence is from a single instance with a single operator, presented as illustration of what these architectural properties can support in practice. Implemented in approximately Gleam on Erlang/OTP. Code, artefacts, and redacted operational logs will be available at https://github.com/seamus-brady/springdrift upon publication.
In introductory presentations of policy gradients, one often derives the REINFORCE estimator using the full trajectory return and then states, by ``causality,'' that the full return may be replaced by the reward-to-go. Although this statement is correct, it is frequently presented at a level of rigor that leaves unclear where the past-reward terms disappear. This short paper isolates that step and gives a mathematically explicit derivation based on prefix trajectory distributions and the score-function identity. The resulting account does not change the estimator. Its contribution is conceptual: instead of presenting reward-to-go as a post hoc unbiased replacement for full return, it shows that reward-to-go arises directly once the objective is decomposed over prefix trajectories. In this formulation, the usual causality argument is recovered as a corollary of the derivation rather than as an additional heuristic principle.
People often optimize for long-term goals in collaboration: A mentor or companion doesn't just answer questions, but also scaffolds learning, tracks progress, and prioritizes the other person's growth over immediate results. In contrast, current AI systems are fundamentally short-sighted collaborators - optimized for providing instant and complete responses, without ever saying no (unless for safety reasons). What are the consequences of this dynamic? Here, through a series of randomized controlled trials on human-AI interactions (N = 1,222), we provide causal evidence for two key consequences of AI assistance: reduced persistence and impairment of unassisted performance. Across a variety of tasks, including mathematical reasoning and reading comprehension, we find that although AI assistance improves performance in the short-term, people perform significantly worse without AI and are more likely to give up. Notably, these effects emerge after only brief interactions with AI (approximately 10 minutes). These findings are particularly concerning because persistence is foundational to skill acquisition and is one of the strongest predictors of long-term learning. We posit that persistence is reduced because AI conditions people to expect immediate answers, thereby denying them the experience of working through challenges on their own. These results suggest the need for AI model development to prioritize scaffolding long-term competence alongside immediate task completion.
The accelerating adoption of large language models, retrieval-augmented generation pipelines, and multi-agent AI workflows has created a structural governance crisis. Organizations cannot govern what they cannot see, and existing compliance methodologies built for deterministic web applications provide no mechanism for discovering or continuously validating AI systems that emerge across engineering teams without formal oversight. The result is a widening trust gap between what regulators demand as proof of AI governance maturity and what organizations can demonstrate. This paper proposes AI Trust OS, a governance architecture for continuous, autonomous AI observability and zero-trust compliance. AI Trust OS reconceptualizes compliance as an always-on, telemetry-driven operating layer in which AI systems are discovered through observability signals, control assertions are collected by automated probes, and trust artifacts are synthesized continuously. The framework rests on four principles: proactive discovery, telemetry evidence over manual attestation, continuous posture over point-in-time audit, and architecture-backed proof over policy-document trust. The framework operates through a zero-trust telemetry boundary in which ephemeral read-only probes validate structural metadata without ingressing source code or payload-level PII. An AI Observability Extractor Agent scans LangSmith and Datadog LLM telemetry, automatically registering undocumented AI systems and shifting governance from organizational self-report to empirical machine observation. Evaluated across ISO 42001, the EU AI Act, SOC 2, GDPR, and HIPAA, the paper argues that telemetry-first AI governance represents a categorical architectural shift in how enterprise trust is produced and demonstrated.
AI agents, autonomous digital actors, need agent-native protocols; existing methods include GUI automation and MCP-based skills, with defects of high token consumption, fragmented interaction, inadequate security, due to lacking a unified top-level framework and key components, each independent module flawed. To address these issues, we present ANX, an open, extensible, verifiable agent-native protocol and top-level framework integrating CLI, Skill, MCP, resolving pain points via protocol innovation, architectural optimization and tool supplementation. Its four core innovations: 1) Agent-native design (ANX Config, Markup, CLI) with high information density, flexibility and strong adaptability to reduce tokens and eliminate inconsistencies; 2) Human-agent interaction combining Skill's flexibility for dual rendering as agent-executable instructions and human-readable UI; 3) MCP-supported on-demand lightweight apps without pre-registration; 4) ANX Markup-enabled machine-executable SOPs eliminating ambiguity for reliable long-horizon tasks and multi-agent collaboration. As the first in a series, we focus on ANX's design, present its 3EX decoupled architecture with ANXHub and preliminary feasibility analysis and experimental validation. ANX ensures native security: LLM-bypassed UI-to-Core communication keeps sensitive data out of agent context; human-only confirmation prevents automated misuse. Form-filling experiments with Qwen3.5-plus/GPT-4o show ANX reduces tokens by 47.3% (Qwen3.5-plus) and 55.6% (GPT-4o) vs MCP-based skills, 57.1% (Qwen3.5-plus) and 66.3% (GPT-4o) vs GUI automation, and shortens execution time by 58.1% and 57.7% vs MCP-based skills.
Large Language Model (LLM) agents require persistent memory to maintain personalization, factual continuity, and long-horizon reasoning, yet standard context-window and retrieval-augmented generation (RAG) pipelines degrade over multi-session interactions. We present MemMachine, an open-source memory system that integrates short-term, long-term episodic, and profile memory within a ground-truth-preserving architecture that stores entire conversational episodes and reduces lossy LLM-based extraction. MemMachine uses contextualized retrieval that expands nucleus matches with surrounding context, improving recall when relevant evidence spans multiple dialogue turns. Across benchmarks, MemMachine achieves strong accuracy-efficiency tradeoffs: on LoCoMo it reaches 0.9169 using gpt4.1-mini; on LongMemEvalS (ICLR 2025), a six-dimension ablation yields 93.0 percent accuracy, with retrieval-stage optimizations -- retrieval depth tuning (+4.2 percent), context formatting (+2.0 percent), search prompt design (+1.8 percent), and query bias correction (+1.4 percent) -- outperforming ingestion-stage gains such as sentence chunking (+0.8 percent). GPT-5-mini exceeds GPT-5 by 2.6 percent when paired with optimized prompts, making it the most cost-efficient setup. Compared to Mem0, MemMachine uses roughly 80 percent fewer input tokens under matched conditions. A companion Retrieval Agent adaptively routes queries among direct retrieval, parallel decomposition, or iterative chain-of-query strategies, achieving 93.2 percent on HotpotQA-hard and 92.6 percent on WikiMultiHop under randomized-noise conditions. These results show that preserving episodic ground truth while layering adaptive retrieval yields robust, efficient long-term memory for personalized LLM agents.
Ensuring that artificial intelligence (AI) systems satisfy formal safety and policy constraints is a central challenge in safety-critical domains. While limitations of verification are often attributed to combinatorial complexity and model expressiveness, we show that they arise from intrinsic information-theoretic limits. We formalize policy compliance as a verification problem over encoded system behaviors and analyze it using Kolmogorov complexity. We prove an incompleteness result: for any fixed sound computably enumerable verifier, there exists a threshold beyond which true policy-compliant instances cannot be certified once their complexity exceeds that threshold. Consequently, no finite formal verifier can certify all policy-compliant instances of arbitrarily high complexity. This reveals a fundamental limitation of AI safety verification independent of computational resources, and motivates proof-carrying approaches that provide instance-level correctness guarantees.
This work addresses challenges in evaluating adaptive artificial intelligence (AI) models for medical devices, where iterative updates to both models and evaluation datasets complicate performance assessment. We introduce a novel approach with three complementary measurements: learning (model improvement on current data), potential (dataset-driven performance shifts), and retention (knowledge preservation across modification steps), to disentangle performance changes caused by model adaptations versus dynamic environments. Case studies using simulated population shifts demonstrate the approach's utility: gradual transitions enable stable learning and retention, while rapid shifts reveal trade-offs between plasticity and stability. These measurements provide practical insights for regulatory science, enabling rigorous assessment of the safety and effectiveness of adaptive AI systems over sequential modifications.
Proprietary AI systems have recently demonstrated impressive capabilities on complex proof-based problems, with gold-level performance reported at the 2025 International Mathematical Olympiad (IMO). However, the training pipelines behind these systems remain largely undisclosed, and their reliance on large "internal" models and scaffolds makes them expensive to run, difficult to reproduce, and hard to study or improve upon. This raises a central question: can small, open models also be trained to achieve competitive reasoning performance on difficult Olympiad-level math? In this paper, we answer this question by building QED-Nano, a 4B model post-trained for Olympiad-level proofs. Our training recipe has three stages: (1) supervised fine-tuning to imbue good proof-writing styles by distilling from DeepSeek-Math-V2, (2) reinforcement learning (RL) with rubric-based rewards, and (3) expanding RL with a reasoning cache, which decomposes long proofs into iterative summarize-and-refine cycles and enables stronger test-time reasoning. QED-Nano surpasses the proof-generation performance of much larger open models, including Nomos-1 and GPT-OSS-120B, and approaches the performance of proprietary models like Gemini 3 Pro, at a fraction of the inference cost. To support further research on open mathematical reasoning, we release the full QED-Nano pipeline, including the QED-Nano and QED-Nano-SFT models, the FineProofs-SFT and FineProofs-RL datasets, and the training and evaluation code.
Synthesizing unstructured research materials into manuscripts is an essential yet under-explored challenge in AI-driven scientific discovery. Existing autonomous writers are rigidly coupled to specific experimental pipelines, and produce superficial literature reviews. We introduce PaperOrchestra, a multi-agent framework for automated AI research paper writing. It flexibly transforms unconstrained pre-writing materials into submission-ready LaTeX manuscripts, including comprehensive literature synthesis and generated visuals, such as plots and conceptual diagrams. To evaluate performance, we present PaperWritingBench, the first standardized benchmark of reverse-engineered raw materials from 200 top-tier AI conference papers, alongside a comprehensive suite of automated evaluators. In side-by-side human evaluations, PaperOrchestra significantly outperforms autonomous baselines, achieving an absolute win rate margin of 50%-68% in literature review quality, and 14%-38% in overall manuscript quality.
Simulation is essential for autonomous driving, yet current frameworks often model vehicles as rigid assets and fail to capture part-level articulation. With perception algorithms increasingly leveraging dynamics such as wheel steering or door opening, realistic simulation requires animatable vehicle representations. Existing CAD-based pipelines are limited by library coverage and fixed templates, preventing faithful reconstruction of in-the-wild instances. We propose a generative framework that, from a single image or sparse multi-view input, synthesizes an animatable 3D Gaussian vehicle. Our method addresses two challenges: (i) large 3D asset generators are optimized for static quality but not articulation, leading to distortions at part boundaries when animated; and (ii) segmentation alone cannot provide the kinematic parameters required for motion. To overcome this, we introduce a part-edge refinement module that enforces exclusive Gaussian ownership and a kinematic reasoning head that predicts joint positions and hinge axes of movable parts. Together, these components enable faithful part-aware simulation, bridging the gap between static generation and animatable vehicle models.
Multi-objective retrosynthesis planning is a critical chemistry task requiring dynamic balancing of quality, safety, and cost objectives. Language model-based multi-agent systems (MAS) offer a promising approach for this task: leveraging interactions of specialized agents to incorporate multiple objectives into retrosynthesis planning. We present MMORF, a framework for constructing MAS for multi-objective retrosynthesis planning. MMORF features modular agentic components, which can be flexibly combined and configured into different systems, enabling principled evaluation and comparison of different system designs. Using MMORF, we construct two representative MAS: MASIL and RFAS. On a newly curated benchmark consisting of 218 multi-objective retrosynthesis planning tasks, MASIL achieves strong safety and cost metrics on soft-constraint tasks, frequently Pareto-dominating baseline routes, while RFAS achieves a 48.6% success rate on hard-constraint tasks, outperforming state-of-the-art baselines. Together, these results show the effectiveness of MMORF as a foundational framework for exploring MAS for multi-objective retrosynthesis planning. Code and data are available at https://anonymous.4open.science/r/MMORF/.
We introduce MedGemma 1.5 4B, the latest model in the MedGemma collection. MedGemma 1.5 expands on MedGemma 1 by integrating additional capabilities: high-dimensional medical imaging (CT/MRI volumes and histopathology whole slide images), anatomical localization via bounding boxes, multi-timepoint chest X-ray analysis, and improved medical document understanding (lab reports, electronic health records). We detail the innovations required to enable these modalities within a single architecture, including new training data, long-context 3D volume slicing, and whole-slide pathology sampling. Compared to MedGemma 1 4B, MedGemma 1.5 4B demonstrates significant gains in these new areas, improving 3D MRI condition classification accuracy by 11% and 3D CT condition classification by 3% (absolute improvements). In whole slide pathology imaging, MedGemma 1.5 4B achieves a 47% macro F1 gain. Additionally, it improves anatomical localization with a 35% increase in Intersection over Union on chest X-rays and achieves a 4% macro accuracy for longitudinal (multi-timepoint) chest x-ray analysis. Beyond its improved multimodal performance over MedGemma 1, MedGemma 1.5 improves on text-based clinical knowledge and reasoning, improving by 5% on MedQA accuracy and 22% on EHRQA accuracy. It also achieves an average of 18% macro F1 on 4 different lab report information extraction datasets (EHR Datasets 2, 3, 4, and Mendeley Clinical Laboratory Test Reports). Taken together, MedGemma 1.5 serves as a robust, open resource for the community, designed as an improved foundation on which developers can create the next generation of medical AI systems. Resources and tutorials for building upon MedGemma 1.5 can be found at https://goo.gle/MedGemma.
Clinical diagnosis requires sequential evidence acquisition under uncertainty. However, most Large Language Model (LLM) based diagnostic systems assume fully observed patient information and therefore do not explicitly model how clinical evidence should be sequentially acquired over time. Even when diagnosis is formulated as a sequential decision process, it is still challenging to learn effective diagnostic trajectories. This is because the space of possible evidence-acquisition paths is relatively large, while clinical datasets rarely provide explicit supervision information for desirable diagnostic paths. To this end, we formulate sequential diagnosis as a Latent Diagnostic Trajectory Learning (LDTL) framework based on a planning LLM agent and a diagnostic LLM agent. For the diagnostic LLM agent, diagnostic action sequences are treated as latent paths and we introduce a posterior distribution that prioritizes trajectories providing more diagnostic information. The planning LLM agent is then trained to follow this distribution, encouraging coherent diagnostic trajectories that progressively reduce uncertainty. Experiments on the MIMIC-CDM benchmark demonstrate that our proposed LDTL framework outperforms existing baselines in diagnostic accuracy under a sequential clinical diagnosis setting, while requiring fewer diagnostic tests. Furthermore, ablation studies highlight the critical role of trajectory-level posterior alignment in achieving these improvements.
Fuzzy Cognitive Maps constitute a neuro-symbolic paradigm for modeling complex dynamic systems, widely adopted for their inherent interpretability and recurrent inference capabilities. However, the standard FCM formulation, characterized by scalar synaptic weights and monotonic activation functions, is fundamentally constrained in modeling non-monotonic causal dependencies, thereby limiting its efficacy in systems governed by saturation effects or periodic dynamics. To overcome this topological restriction, this research proposes the Kolmogorov-Arnold Fuzzy Cognitive Map (KA-FCM), a novel architecture that redefines the causal transmission mechanism. Drawing upon the Kolmogorov-Arnold representation theorem, static scalar weights are replaced with learnable, univariate B-spline functions located on the model edges. This fundamental modification shifts the non-linearity from the nodes' aggregation phase directly to the causal influence phase. This modification allows for the modeling of arbitrary, non-monotonic causal relationships without increasing the graph density or introducing hidden layers. The proposed architecture is validated against both baselines (standard FCM trained with Particle Swarm Optimization) and universal black-box approximators (Multi-Layer Perceptron) across three distinct domains: non-monotonic inference (Yerkes-Dodson law), symbolic regression, and chaotic time-series forecasting. Experimental results demonstrate that KA-FCMs significantly outperform conventional architectures and achieve competitive accuracy relative to MLPs, while preserving graph- based interpretability and enabling the explicit extraction of mathematical laws from the learned edges.
As artificial intelligence systems (AIs) become increasingly produced by recursive self-improvement, a form of evolution may emerge, in which the traits of AI systems are shaped by the success of earlier AIs in designing and propagating their descendants. There is a rich mathematical theory modeling how behavioral traits are shaped by biological evolution, but AI evolution will be radically different: biological DNA mutations are random and approximately reversible, but descendant design in AIs will be strongly directed. Here we develop a mathematical model of evolution in self-designing AI systems, replacing random mutations with a directed tree of possible AI programs. Current programs determine the design of their descendants, while humans retain partial control through a "fitness function" that allocates limited computational resources across lineages. We show that evolutionary dynamics reflects not just current fitness but factors related to the long-run growth potential of descendant lineages. Without further assumptions, fitness need not increase over time. However, assuming bounded fitness and a fixed probability that any AI reproduces a "locked" copy of itself, we show that fitness concentrates on the maximum reachable value. We consider the implications of this for AI alignment, specifically for cases where fitness and human utility are not perfectly correlated. We show in an additive model that if deception increases fitness beyond genuine utility, evolution will select for deception. This risk could be mitigated if reproduction is based on purely objective criteria, rather than human judgment.
Computer-Use Agents (CUAs) leverage large language models to execute GUI operations on desktop environments, yet they generate actions without evaluating action quality, leading to irreversible errors that cascade through subsequent steps. We propose IntentScore, a plan-aware reward model that learns to score candidate actions from 398K offline GUI interaction steps spanning three operating systems. IntentScore trains with two complementary objectives: contrastive alignment for state-action relevance and margin ranking for action correctness. Architecturally, it embeds each candidate's planning intent in the action encoder, enabling discrimination between candidates with similar actions but different rationales. IntentScore achieves 97.5% pairwise discrimination accuracy on held-out evaluation. Deployed as a re-ranker for Agent S3 on OSWorld, an environment entirely unseen during training, IntentScore improves task success rate by 6.9 points, demonstrating that reward estimation learned from heterogeneous offline trajectories generalizes to unseen agents and task distributions.
Reconfigurable Intelligent Surfaces (RIS) are pivotal for next-generation smart radio environments, yet their practical deployment is severely bottlenecked by the intractable computational overhead of Channel State Information (CSI) estimation. To bypass this fundamental physical-layer barrier, we propose an AI-native, data-driven paradigm that replaces complex channel modeling with spatial intelligence. This paper presents a fully autonomous Multi-Agent Reinforcement Learning (MARL) framework to control mechanically adjustable metallic reflector arrays. By mapping high-dimensional mechanical constraints to a reduced-order virtual focal point space, we deploy a Centralized Training with Decentralized Execution (CTDE) architecture. Using Multi-Agent Proximal Policy Optimization (MAPPO), our decentralized agents learn cooperative beam-focusing strategies relying on user coordinates, achieving CSI-free operation. High-fidelity ray-tracing simulations in dynamic non-line-of-sight (NLOS) environments demonstrate that this multi-agent approach rapidly adapts to user mobility, yielding up to a 26.86 dB enhancement over static flat reflectors and outperforming single-agent and hardware-constrained DRL baselines in both spatial selectivity and temporal stability. Crucially, the learned policies exhibit good deployment resilience, sustaining stable signal coverage even under 1.0-meter localization noise. These results validate the efficacy of MARL-driven spatial abstractions as a scalable, highly practical pathway toward AI-empowered wireless networks.
Reconfigurable Intelligent Surfaces (RIS) has a potential to engineer smart radio environments for next-generation millimeter-wave (mmWave) networks. However, the prohibitive computational overhead of Channel State Information (CSI) estimation and the dimensionality explosion inherent in centralized optimization severely hinder practical large-scale deployments. To overcome these bottlenecks, we introduce a ``CSI-free" paradigm powered by a Hierarchical Multi-Agent Reinforcement Learning (HMARL) architecture to control mechanically reconfigurable reflective surfaces. By substituting pilot-based channel estimation with accessible user localization data, our framework leverages spatial intelligence for macro-scale wave propagation management. The control problem is decomposed into a two-tier neural architecture: a high-level controller executes temporally extended, discrete user-to-reflector allocations, while low-level controllers autonomously optimize continuous focal points utilizing Multi-Agent Proximal Policy Optimization (MAPPO) under a Centralized Training with Decentralized Execution (CTDE) scheme. Comprehensive deterministic ray-tracing evaluations demonstrate that this hierarchical framework achieves massive RSSI improvements of up to 7.79 dB over centralized baselines. Furthermore, the system exhibits robust multi-user scalability and maintains highly resilient beam-focusing performance under practical sub-meter localization tracking errors. By eliminating CSI overhead while maintaining high-fidelity signal redirection, this work establishes a scalable and cost-effective blueprint for intelligent wireless environments.