The Inference Report

This paper develops procedures for nonparametric goodness-of-fit testing under covariate shift, where labelled data are drawn from a source population but goodness-of-fit is evaluated for a target population. The distribution mismatch is quantified by either a bounded moment condition or a sub-exponential tail condition on the target-to-source density ratio. Our method combines truncated importance-weighting kernel ridge regression with a multiplier bootstrap to construct confidence sets for the regression function. The truncation stabilizes the importance- weighting kernel ridge regression as well as the bootstrap calibration, making our approach applicable even when the density ratio has heavy tails. We prove nonasymptotic validity and sharpness of the resulting confidence sets under suitable operator compatibility conditions, and establish explicit error rates for coverage probability under specific conditions on the target- to-source density ratio and on the spectral decay of the kernel integral operator. Numerical experiments corroborate our theoretical findings.

This paper develops procedures for nonparametric goodness-of-fit testing under covariate shift, where labelled data are drawn from a source population but goodness-of-fit is evaluated for a target population. The distribution mismatch is quantified by either a bounded moment condition or a sub-exponential tail condition on the target-to-source density ratio. Our method combines truncated importance-weighting kernel ridge regression with a multiplier bootstrap to construct confidence sets for the regression function. The truncation stabilizes the importance- weighting kernel ridge regression as well as the bootstrap calibration, making our approach applicable even when the density ratio has heavy tails. We prove nonasymptotic validity and sharpness of the resulting confidence sets under suitable operator compatibility conditions, and establish explicit error rates for coverage probability under specific conditions on the target- to-source density ratio and on the spectral decay of the kernel integral operator. Numerical experiments corroborate our theoretical findings.

Multimodal supervised learning seeks to leverage multiple heterogeneous data sources to improve predictive performance. A central challenge is determining the fusion granularity across modalities: over-integration may amplify noise while under-integration fails to exploit cross-modal dependence. Existing approaches rely on pre-specified fusion architectures, from early to late fusion, that may not adapt to the underlying dependence structure among modalities. We propose DAIF, a data adaptive intermediate fusion framework that combines random matrix theory and non-parametric dependence measures to learn fusion structure directly from data. We operate under a Bayesian multimodal factor model where the prior on the latent factors determines the cross-modal dependence. Our method clusters modalities based on estimated intermodal dependence, then performs clusterwise empirical Bayes estimation of the priors. These estimated priors are used to construct denoisers within an approximate message passing (AMP) framework, yielding denoised low-dimensional features that borrow strength across related modalities while preserving modality-specific signal. The resulting embeddings are used for downstream supervised prediction. We evaluate the framework through simulations under varying dependence structures and signal regimes, comparing against several benchmark methods, and demonstrate its practical utility on two multimodal datasets, namely a trimodal TEA-seq dataset (Swanson et al., 2021) and TCGA-BRCA dataset (Goldman et al., 2020). In the first example, we predict the expression level of a T-cell differentiation marker protein and in the second case we analyze patient survival prediction based on multimodal information. Our method competes with or outperforms the state-of-the-art techniques in both prediction problems, demonstrating its versatility across diverse supervised learning tasks.

In recent years, numerous open-source software libraries have been developed for computing sets of features from univariate time series. The type and number of features vary across these feature sets, which have been constructed with varying disciplinary perspectives on quantifying structure in time-series data. To date, the relative strengths and weaknesses of these feature sets on time-series classification problems remains largely unexplored. Here we aimed to understand the relative performance of six open-source feature sets and three baseline feature sets (based on distributional and/or basic spectral structure) across 124 univariate time-series classification problems using a normalization-based approach to problem-level benchmarking that better indexes the relative strengths and weaknesses of different algorithms compared to prior rank-based approaches. Despite their dramatic differences in size, composition, and computation time, we found that feature sets performed relatively similarly overall (85.3% of pairwise comparisons resulted in ties), with the largest feature set, tsfresh, exhibiting the strongest overall performance (29.03% wins across all pairwise comparisons against other feature sets). We also highlighted specific problems on which the specific composition of a given feature set gave it a substantial performance advantage or disadvantage, and problems where simple baselines comprised of Fourier coefficients and quantiles were sufficient to achieve strong performance. Our results demonstrate the need to consider problem-level performance when benchmarking time-series feature sets, and highlight the importance of feature make-up in driving relative classification performance.

Detecting a change in a multivariate series answers only the first of two questions; the operational question is which coordinates changed. Existing answers are incomplete. Block-level procedures certify predefined groups of coordinates under an additive union bound, high-dimensional variable-selection methods return interpretable rankings without error guarantees, and the post-detection inference literature controls error along the time axis rather than across coordinates. We propose ARM (Attribution by Rank Maxima), a wrapper that accepts a changepoint located by an arbitrary detector and returns the set of coordinates certified to have changed, each carrying a location or scale type label. ARM scores each coordinate by a max-over-splits rank statistic. Because this statistic dominates the corresponding statistic at the estimated split, the resulting certificate is invariant to the manner, and to the accuracy, of the changepoint estimate. Three finite-sample guarantees follow from within-coordinate ranks alone: per-coordinate validity under any detector; exact family-wise error control through a Westfall--Young joint permutation that preserves cross-coordinate dependence, with a fully distribution-free Holm fallback; and false discovery rate control under arbitrary coordinate dependence in high dimensions through Benjamini--Yekutieli and e-BH. In simulations, naive per-coordinate testing at the estimated changepoint inflates its family-wise error beyond $0.66$ as the dimension grows, whereas ARM maintains the nominal level while retaining validity under heavy tails, power in high dimensions, and accurate type labels. On five financial series surrounding the 2008 collapse, ARM attributes a scale change to every asset class and excludes injected control coordinates.

Regression estimates from observational data can depend on specification under multicollinearity, while sequential sums of squares (SS) depend on term order. We introduce Retrospective Orthogonal Design (ROD), which reconstructs conditional mean surfaces on a probability-balanced lattice. ROD preserves observed cell means, completes unsupported cells, applies weighted tensor-product contrasts, and evaluates the reconstructed surface through piecewise-affine interpolation over Freudenthal polyhedra. Resolution and completion are selected jointly by validation among rank-admissible candidates, followed by refitting and evaluation on an untouched test set. For an admissible lattice, $\mathbf{X}^{\top}\mathbf{W}\mathbf{X}=c\mathbf{I}$, yielding specification-invariant contrast effects and unique, order-independent SS within the retained contrast space. Response-free projection calibration maps the fixed reconstruction onto a declared scientific basis and corrects finite-resolution recovery loss. Across 6,480 simulation conditions spanning nine data-generating processes, ROD matched or exceeded polynomial regression in five processes and performed strongest on threshold, sign-interaction, and localized surfaces. For the quadratic-interaction process, mean out-of-sample $R^2$ differed by only $0.0001$, while calibrated coefficient bias remained small across prespecified targets. A Rao-based information adjustment provides dependence-aware sample-size guidance for ROD planning. In a weighted Mincer application, ROD produced the highest out-of-sample $R^2$ point estimate, with substantial interval overlap with polynomial regression, and provided exhaustive SS allocations invariant to term-entry order.